To be short, yes it can.
At more length - in order to publish to the Wii, you must become a certified developer by Nintendo, which is actually quite the process. (It took the company I work for months to be accepted and we were actually denied once initially)
From there you have to purchase the Nintendo Wii Development kit from Nintendo and you will have to contact Unity and purchase the Wii-compatible version of Unity.
Also, Unity announced sometime in the not-too-distant future we will be able to develop for XBox360 as well.
answered Dec 02 '09 at 03:37 AM
answered Dec 11 '09 at 12:36 PM
Thank you. We have already contacted Nintendo about becoming a registered developer. How much is the Nintendo Wii Development Compatible version of Unity? Also for the XBox360 too?
Is the game development more programming intensive or drag n' drop? If it is programming what language? C++ or C#?
answered Dec 02 '09 at 03:56 AM