How do I disable collision for a mouse click

i have my camera --------------- up

and my hidden collision in ----- middle

and my target to click in ------ down

so can i DISABLE a collision for a MOUSE CLICK please

i want to make the collision response to everything WITHOUT the mouse click

Dude, this question makes no sense! Are you confusing collision with collider? Collision is what happens when a collider hits another one. Could you be trying to hit with a raycast something that is hidden by another object? If this is the case, you could simply remove the collider from the object that obscures the target. Another solution would be to move the obscuring object to the Ignore Raycast layer.

You can tell a Physic.Raycast which layer it should ignore.