Built game not working. Again.

So, after i thought i figured it out, suddenly it starts doing exact same thing it did last time; Simply put, not starting at all. Last time disabling the launcher fixed this. Now the same problem is back, and tweaking with the launcher does nothing anymore.

While building the game, everything goes smooth, no errors no nothing.
But once i double click the games EXE, my mouse cursor just keeps spinning thus loading it. And nothing ever happens. I cannot delete the the EXE. since my PC says they are open in SYSTEM after ive launched them, so i have to restart the whole PC to delete them, obviously.
No log files can be found either.

Using newest Unity Personal, and Windows 10 64bit.

@Kyle_L I found out that few things prevented this. First, disable Launcher completely. Second reset Quality settings to originals if tampered with. Those fixed it for me.